Molecular Envelope Technology - Principle
Molecular Envelope Technology (MET) nanoparticles are engineered from biocompatible polymers. By tailoring of key properties such as molecular weight, and hydrophilic/ hydrophobic substituents (1) MET polymers are synthesised (2) which self-assemble into highly stable small nanoparticles (4). The polymers wrap around and incorporate hydrophobic drugs and peptides (5) creating a protective molecular envelope. The drugs can be loaded with high efficacy into the resulting stable and small (~50 nm) MET nanoparticles (6).